For more than three decades, while its writer's world fame increased, Queer remained unpublished because of its forthright depiction of homosexual longings. Set in the corrupt and spectral Mexico City of the forties, Queer is the story of William Lee, a man afflicted with both acute heroin withdrawal and romantic and sexual yearnings for an indifferent user named Eugene Allerton. The narrative is punctuated by Lee's outrageous "routines" — brilliant comic monologues that foreshadow Naked Lunch —yet the atmosphere is heavy with foreboding.

In his extraordinary introduction, Burroughs reflects on the shattering events in his life that lay behind this work.